INT-06

Endogenous Interferents:
Beyond Hemolysis, Lipemia, and Icterus

ASSURANCE™ Test Kits from Sun Diagnostics.

Certainly the “big 3” are important, but other endogenous metabolites may also interfere with common laboratory tests. Among the endogenous interferents, these seven circulate at relatively high concentration and can interfere with spectrophotometric assays: creatinine, glucose, glycerol, lactate, pyruvate, uric acid, and urea. CLSI has recommended concentrations and protocols for testing these potential interferents (Interference Testing in Clinical Chemistry; Approved Guidelines (EP07-A2), and Sun Diagnostics now has a kit to simplify testing for these endogenous metabolites: INT-06. The metabolites come in individual vials at 20-fold the CLSI recommended test concentrations so that they are easily spiked into serum or urine pools for analysis.

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Items for Download:

• Interference Testing Protocol

• Data Analysis Tools

ASSURANCE^™ Endogenouse Interferents Test Kit PN: INT-06 Price: $740 Includes: One vial of each component, 1ml Individual Interferents $115/vial
Interferent	ASSURANCE^™ Concentration*	Component PN
CREATININE	300 mg/dL	INT-06C
GLUCOSE	20,000 mg/dL	INT-06GLU
GLYCEROL	340 mg/dL	INT-06GLY
LACTATE	1,800 mg/dL	INT-06LAC
PYRUVATE	100 mg/dL	INT-06PYR
BLOOD UREA NITROGEN	2,400 mg/dL	INT-06BUN
URIC ACID	470 mg/dL	INT-06UA (Includes NaOH for control)

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Ike Skelton

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